Nuclear Arc Puts a Brake on Cocaine-Induced Chromatin Remodeling and Behaviors
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چکیده
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Chromatin remodeling contributes to healthy adaptations, including learning and memory, and to diseases, including schizophrenia. Dr. Eric Nestler and colleagues at the University of Texas Southwestern Medical Center and Harvard Medical School revealed its role in cocaine pathology. In a series of experiments with rats, they demonstrated that cocaine-induced chromatin remodeling increases the p...
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ژورنال
عنوان ژورنال: Biological Psychiatry
سال: 2017
ISSN: 0006-3223
DOI: 10.1016/j.biopsych.2017.01.007